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Depression is because not enough people drink water

AI summary:

Tryptophan converts to serotonin/melatonin; serotonin’s role in depression is overstated. Drug industry and government shaped biased narratives favoring SSRIs. Serotonin affects many systems—movement, immune, metabolism, reproduction—often harming when excessive. Anti-serotonin agents show therapeutic potential for various disorders beyond mood.

Excess serotonin is often blamed for depression, but evidence is mixed: some antidepressants lower serotonin, others don't. Serotonin (and related hormones) affects energy metabolism, learning, inflammation, movement disorders, and female-biased diseases. Antiserotonin drugs (e.g., methysergide, bromocriptine) show therapeutic potential; current serotonin-focused drug narratives are oversimplified.

Most sources argue serotonin’s role in mood is overstated: excess serotonin can impair energy metabolism, learning, and cause "learned helplessness," while anti‑serotonin agents (e.g., LSD derivatives, bromocriptine, methysergide) show therapeutic effects. Drug‑industry and government narratives promoted SSRIs; alternatives (thyroid, progesterone, antiserotonin, nutrition) may better address serotonin‑excess syndromes.
 
im drinking coke
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Africa is very sunny but it has the highest suicide rate
What effect do melanin and sunscreen have on vitamin D levels? (https://www.ewg.org/news-insights/news/2022/05/what-effect-do-melanin-and-sunscreen-have-vitamin-d-levels)
The amount of melanin in the skin affects vitamin D status because the skin depends on UV rays to synthesize vitamin D, and darker skin inhibits its production.

Even if it weren't for melanin, vitamin D wouldn't help with the depressive life of a subsaharan noob. You have to amount malnutrition and arid climates too
 
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